Egbert P R, Chan C C, Winter F C
J Pediatr Ophthalmol. 1976 Nov-Dec;13(6):336-9.
Flat preparations of the retina were prepared by trypsin digestion in ten cases of Coats' disease. All of the patients were young males with advanced disease leading to enucleation. All eyes showed marked abnormalities in the arterioles, venules, and capillaries. The findings most characteristic of Coats' disease were large aneurysms and thick PAS positive deposits in vessel walls. The aneurysms ranged from 50 to 350 microns and frequently formed large sausage-like or beaded out-pouchings and were sometimes situated on shunt vessels. Other findings frequently seen, but not specific for Coats' disease, were capillary dilatation, small aneurysms, hypocellular vessel walls, and fibrous strands.
对10例科茨病患者的视网膜进行胰蛋白酶消化后制备扁平标本。所有患者均为年轻男性，患有晚期疾病并导致眼球摘除。所有眼睛的小动脉、小静脉和毛细血管均显示出明显异常。科茨病最具特征性的表现是大动脉瘤和血管壁上厚厚的PAS阳性沉积物。动脉瘤大小在50至350微米之间，常形成大的香肠状或串珠状外突，有时位于分流血管上。其他常见但并非科茨病特有的表现包括毛细血管扩张、小动脉瘤、血管壁细胞减少和纤维条索。
