Trosić A, Sterijev K, Tarle M, Ljubojević N, Pajtler M
Jugosl Ginekol Opstet. 1981 May-Aug;21(3-4):75-8.
A case of primary, insular, argentaffin carcinoid tumor (argentaffinoma) of the left ovary, arising in a bening cystic teratoma in a 60-year-old woman is reported. The tumor was not accompanied by any signs of the carcinoid syndrome despite a large volume, prominent acinar differentiation, and strong argentaffinity. Considering the morphologic carcinoid classification by Soga and Tazawa, the case had a mixed A + C pattern. A few Paneth-like cells and a few small calcifications in the stroma were present. Microscopic, ultrastructural, and histochemical findings were identical with those of carcinoids arising in midgut derivatives. There were small mucinous areas about 1.5 cm in diameter. Microscopic examination revealed pools of mucin with more of less disintegrated acini. This morphologic feature was not as yet reported in the insular carcinoid tumor. The patient feels well one and half year after hysterectomy and bilateral salpingo-oophorectomy, without any signs of metastatic disease.
本文报告了一例60岁女性左卵巢原发性岛状嗜银性类癌肿瘤(嗜银细胞瘤),该肿瘤起源于良性囊性畸胎瘤。尽管肿瘤体积较大、腺泡分化明显且嗜银性强,但未伴有任何类癌综合征的体征。根据Soga和Tazawa的形态学类癌分类,该病例具有混合A + C模式。间质中存在一些潘氏样细胞和少量小钙化灶。显微镜、超微结构和组织化学检查结果与中肠衍生物来源的类癌相同。有直径约1.5厘米的小黏液区。显微镜检查显示有黏液池,腺泡或多或少已崩解。这种形态学特征在岛状类癌肿瘤中尚未见报道。患者在子宫切除及双侧输卵管卵巢切除术后一年半情况良好,无任何转移疾病的迹象。