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卵巢成熟性囊性畸胎瘤中发生的原发性类癌肿瘤:一例报告

Primary carcinoid tumor arising in a mature cystic teratoma of the ovary: a case report.

作者信息

Guney N, Sayilgan T, Derin D, Ozcan D

机构信息

Department of Medical Oncology, Okmeydam Research and Training Hospital, Istanbul, Turkey.

出版信息

Eur J Gynaecol Oncol. 2009;30(2):223-5.

Abstract

OBJECTIVE

To present an extremely rare case of a primary carcinoid tumor arising in a mature cystic teratoma of the ovary. Malignant transformation of mature cystic teratoma is an uncommon complication occuring in approximately 1-3% of patients with mature cystic teratoma.

CLINICAL PRESENTATION AND INTERVENTION

A 54-year-old woman presented with abdominal swelling and abnormal uterine bleeding. Physical examination revealed a smooth, non-painful, 8-9 cm diameter mass in the right anterior pelvis which was diagnosed histologically as carcinoid tumor arising in a mature cystic teratoma. The patient underwent a total abdominal hysterectomy with bilateral salpingo-oophorectomy and was scheduled for surveillance CT of the abdomen and pelvis at 3-monthly intervals.

CONCLUSION

This case adds to the rare reports in the literature of a carcinoid of low malignant potential occurring in a mature cystic teratoma. The treatment for early-stage ovarian carcinoid tumors confined to one ovary is surgery alone and excellent outcomes can be expected in these cases.

摘要

目的

报告一例极为罕见的起源于卵巢成熟囊性畸胎瘤的原发性类癌肿瘤。成熟囊性畸胎瘤的恶性转化是一种不常见的并发症,约1%-3%的成熟囊性畸胎瘤患者会发生。

临床表现与干预措施

一名54岁女性因腹部肿胀和子宫异常出血前来就诊。体格检查发现右前盆腔有一个直径8-9厘米、表面光滑、无压痛的肿块,经组织学诊断为起源于成熟囊性畸胎瘤的类癌肿瘤。该患者接受了全腹子宫切除术及双侧输卵管卵巢切除术,并计划每3个月进行一次腹部和盆腔的CT监测。

结论

该病例补充了文献中关于成熟囊性畸胎瘤中发生的低恶性潜能类癌的罕见报道。局限于一侧卵巢的早期卵巢类癌肿瘤的治疗方法是单纯手术,这些病例有望获得良好的治疗效果。

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