György L, Orr Z, Dóda M
Acta Physiol Acad Sci Hung. 1981;58(2):163-8.
The inhibitory effect of noradrenaline, dopamine and four dopaminergic agonists on smooth muscle relaxation induced by nerve stimulation was compared in isolated rabbit ileum. All these compounds inhibit the relaxation evoked by nerve stimulation. Their activity decreased in the following order: bromocriptine, noradrenaline, nomifensine, dopamine, piribedil and apomorphine. Yohimbine inhibited the effect of noradrenaline and to a lesser extent that of dopamine, while the antidopamine agent sulpiride abolished the effect of dopamine, apomorphine and nomifensine. The presynaptic action of these compounds is discussed.
在离体兔回肠中比较了去甲肾上腺素、多巴胺和四种多巴胺能激动剂对神经刺激诱导的平滑肌舒张的抑制作用。所有这些化合物均抑制神经刺激诱发的舒张。它们的活性按以下顺序降低：溴隐亭、去甲肾上腺素、诺米芬辛、多巴胺、吡贝地尔和阿扑吗啡。育亨宾抑制去甲肾上腺素的作用，对多巴胺的作用抑制程度较小，而抗多巴胺药舒必利则消除多巴胺、阿扑吗啡和诺米芬辛的作用。讨论了这些化合物的突触前作用。
