Jouannet P, Soufir J C, Ducot B, Spira A, Soumah A, Marson J
Ann Endocrinol (Paris). 1981 Oct-Nov;42(4-5):416-22.
The semen characteristics of 215 fertile men (F = fathers requesting vasectomy) and of 409 infertile men (I) have been analysed under strictly identical conditions. The mean values for volume, sperm concentration, and the percentages of motile, vital and morphologically normal spermatozoa were greater in group F than in I. Seminal variations were much greater in cases of testicular lesions (cryptorchidism, hypotrophy) than in varicocele, although there remains a difference between F and I even after exclusion of all clinical lesions suggesting a role for other factors in the origin of much cases of infertility. Other than in cases of azoospermia, there is no difference in the function of the accessory glands detectable by the assay of seminal biochemical markers: fructose (seminal vesicles) acid phosphatase and citrate (prostate); only L-carnitine (epididymal marker) is elevated in the fertile men, however this difference is only a reflection of the observed difference in sperm concentration in combination with the close correlation between sperm concentration and L-carnitine values.
在严格相同的条件下，对215名有生育能力的男性（F = 请求输精管结扎术的父亲）和409名不育男性（I）的精液特征进行了分析。F组的精液量、精子浓度以及活动精子、有活力精子和形态正常精子的百分比的平均值均高于I组。睾丸病变（隐睾症、发育不全）患者的精液变化比精索静脉曲张患者大得多，尽管在排除所有提示其他因素在许多不育病例起源中起作用的临床病变后，F组和I组之间仍存在差异。除无精子症病例外，通过精液生化标志物检测（果糖（精囊）、酸性磷酸酶和柠檬酸盐（前列腺）），附属腺体的功能没有差异；只有L-肉碱（附睾标志物）在有生育能力的男性中升高，然而，这种差异只是观察到的精子浓度差异的反映，以及精子浓度与L-肉碱值之间的密切相关性。
