苯乙烯聚合工人接触的生物指标。血液和脂肪组织中的苯乙烯以及尿液中的扁桃酸和苯乙醛酸。
Biological indicators of exposure in styrene polymerization workers. Styrene in blood and adipose tissue and mandelic and phenylglyoxylic acids in urine.
作者信息
Wolff M S, Lilis R, Lorimer W V, Selikoff I J
出版信息
Scand J Work Environ Health. 1978;4 Suppl 2:114-8.
The concentrations of mandelic and phenylglyoxylic acids, urinary metabolites of styrene, and styrene in blood were determined for 491 styrene polymerization workers. Styrene in subcutaneous fat was determined for 25 workers. The levels of styrene exposure were estimated to be less than 10 ppm, and urinary metabolite and blood styrene concentrations indicated that significant recent exposure (within 4 h) had occurred among workers in areas of styrene polymerization and styrene monomer production. Styrene analysis of subcutaneous fat suggested that the monomer may have been present for as long as 3 d after exposure, a time when urinary metabolites and blood styrene were almost invariably undetectable. All three biological parameters were correlated with recency of exposure and estimated intensity of exposure within job categories.
对491名苯乙烯聚合工人测定了苯乙醇酸和苯乙醛酸（苯乙烯的尿液代谢物）以及血液中苯乙烯的浓度。对25名工人测定了皮下脂肪中的苯乙烯含量。据估计，苯乙烯暴露水平低于10 ppm，尿液代谢物和血液中苯乙烯浓度表明，在苯乙烯聚合和苯乙烯单体生产区域的工人中最近（4小时内）发生了显著暴露。皮下脂肪的苯乙烯分析表明，暴露后该单体可能存在长达3天，而此时尿液代谢物和血液中的苯乙烯几乎总是检测不到。所有这三个生物学参数都与暴露时间的新近程度以及工作类别内估计的暴露强度相关。
Zotero 插件