Markowitz S, Goldhar S W, Basu P K, Ranadive N S, Carré F, Basu R
Can J Ophthalmol. 1981 Oct;16(4):187-91.
The phagocytic activity of the pigmented epithelium of the bovine retina was studied with an organ culture model. Latex particles coated with immunoglobulin, or bovine rod outer segments, both labelled with radioactive iodine, were the objects to be phagocytosed. Various agents were tested with this model for their effects on phagocytosis by the retinal pigment epithelium. Iodoacetate significantly inhibited phagocytosis, as did penicillin, though to a lesser extent. Concanavalin A and gentamicin enhanced phagocytosis. Dimethyl sulfoxide had no effect. The results with lymphokines were not conclusive.
利用器官培养模型研究了牛视网膜色素上皮的吞噬活性。包被有免疫球蛋白的乳胶颗粒或均用放射性碘标记的牛视杆外段是被吞噬的对象。用该模型测试了各种试剂对视网膜色素上皮吞噬作用的影响。碘乙酸显著抑制吞噬作用，青霉素也有抑制作用，不过程度较轻。伴刀豆球蛋白A和庆大霉素增强了吞噬作用。二甲基亚砜没有作用。关于淋巴因子的结果尚无定论。
