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橡胶轮胎行业工人的死亡率和癌症发病率。

Mortality and cancer morbidity among workers in the rubber tire industry.

作者信息

Delzell E, Louik C, Lewis J, Monson R R

出版信息

Am J Ind Med. 1981;2(3):209-16. doi: 10.1002/ajim.4700020304.

Abstract

A retrospective follow-up study was conducted to evaluate mortality and cancer incidence between 1954 and 1976 among 1,792 white male production workers employed for at least 2 years at a tire manufacturing plant. There were no marked excesses in overall or site-specific cancer deaths or incident cases. Compared to U.S. white males, men employed for at least 10 years experienced small increases in deaths from cancers of the large intestine, pancreas, and lung. Results obtained by comparing observed incident cancer cases to the numbers expected based on age- and calendar time-specific incidence rates of Connecticut males also suggested excesses of these three malignancies. These findings were based on small numbers and therefore do not necessarily indicate causal associations between cancer excesses and employment in the rubber tire industry. However, because the workers studied comprised a relatively young population that may not have experienced the full impact of carcinogenic occupational exposures, further follow-up is warranted.

摘要

开展了一项回顾性随访研究,以评估1954年至1976年间,在一家轮胎制造工厂工作至少2年的1792名白人男性生产工人的死亡率和癌症发病率。总体或特定部位的癌症死亡或发病病例均无明显增加。与美国白人男性相比,工作至少10年的男性患结肠癌、胰腺癌和肺癌的死亡人数略有增加。通过将观察到的癌症发病病例与根据康涅狄格州男性年龄和日历时间特定发病率预期的病例数进行比较,得到的结果也表明这三种恶性肿瘤发病过多。这些发现基于少量样本,因此不一定表明癌症发病过多与在橡胶轮胎行业工作之间存在因果关系。然而,由于所研究的工人构成了一个相对年轻的人群,可能尚未经历致癌职业暴露的全部影响,因此有必要进行进一步的随访。

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