Gentile F, Greco R, Siciliano S, Violini R, Marsico L, Mininni N, Marsico F
G Ital Cardiol. 1981;11(12):1996-2002.
223 patients with a previous myocardial infarction (MI) 29-68 years old, have been studied in a double-blind manner both by 2D-Echocardiography and cineventriculography. 5 cross-sectional views and 2 angiographic projections have been employed in order to assess the presence of aneurysm and the motion of the left ventricle. The left ventricle has been divided into 5 anatomic regions: interventricular septum, anterolateral, posterolateral, apical and inferior walls. By cineangiography an aneurysm was diagnosed in 89 patients (one pseudoaneurysm); by 2D-Echo in 83 patients an aneurysm was diagnosed, whereas in the 6 remaining patients the Echocardiogram was nondiagnostic (specificity 100%, sensitivity 93%). Concerning regional motion characteristics, 997 (89%) of 1115 regions were visualized and 905 (91%) correctly identified according to the angiographic findings. Of 92 discrepancies (9%): 64 were attributed to 2D-Echo (69%) and 28 (31%) were attributed to cineangiography; most of the discrepancies attributed to echo resulted from minor grades of asynergy which caused unresolved disagreements between the Echo and angiography findings. It is concluded that Cross-sectional echocardiography is a valuable tool for the diagnosis of aneurysm of the left ventricle (specificity 100% and sensitivity 93%) and for the study of wall motion characteristics. In cases with generalized abnormality of left ventricle motion, resulting in a picture of congestive cardiomyopathy, 2D-Echo can be a substitute for cineangiography. In all other instances both techniques can provide more complete information on ventricular wall abnormalities.
对223例年龄在29至68岁之间曾患心肌梗死(MI)的患者,采用二维超声心动图和电影心室造影术进行了双盲研究。采用5个横截面视图和2个血管造影投影来评估室壁瘤的存在及左心室的运动情况。左心室被划分为5个解剖区域:室间隔、前外侧壁、后外侧壁、心尖部和下壁。通过电影血管造影术诊断出89例患者存在室壁瘤(1例假性室壁瘤);通过二维超声心动图诊断出83例患者存在室壁瘤,而其余6例患者的超声心动图检查未得出诊断结果(特异性100%,敏感性93%)。关于局部运动特征,1115个区域中的997个(89%)被观察到,并且根据血管造影结果,905个(91%)被正确识别。在92处差异(9%)中:64处归因于二维超声心动图(69%),28处(31%)归因于电影血管造影术;大多数归因于超声心动图的差异是由轻微程度的运动不协调导致的,这种不协调使得超声心动图和血管造影结果之间存在无法解决的分歧。得出的结论是,横截面超声心动图是诊断左心室室壁瘤(特异性100%,敏感性93%)以及研究室壁运动特征的有价值工具。在左心室运动普遍异常导致充血性心肌病表现的病例中,二维超声心动图可替代电影血管造影术。在所有其他情况下,两种技术都能提供关于心室壁异常更完整的信息。