Yau T M
Scan Electron Microsc. 1981;4:47-54.
Although the nucleus appears to represent the primary target for the killing of cells by ionizing radiation, the cell membrane may be another important site for radiation injury and modification of the radiation response. In this paper, the effects of radiation on various membrane-associated parameters which are expected to affect cellular viability or function are reviewed. These include the effect of radiation on membrane transport, lectin or hormone receptor sites, cell surface electrokinetics, cell membrane fluidity, cell surface topography, etc. Alternative biochemical mechanisms that may account for the effects of radiation on cell membrane in general will also be discussed.
虽然细胞核似乎是电离辐射杀死细胞的主要靶点，但细胞膜可能是辐射损伤和辐射反应调节的另一个重要部位。本文综述了辐射对各种预期会影响细胞活力或功能的膜相关参数的影响。这些参数包括辐射对膜转运、凝集素或激素受体位点、细胞表面电动现象、细胞膜流动性、细胞表面形貌等的影响。文中还将讨论可能解释辐射对细胞膜一般影响的其他生化机制。
