Hecker J F, Edwards R O
J Biomed Mater Res. 1981 Jan;15(1):1-7. doi: 10.1002/jbm.820150104.
Tubings extruded from one batch of polyvinylchloride resin at five temperatures ranging from 110 to 205 degrees C were tested for thrombogenicity in the saphenous vein and aorta of sheep. There was more thrombus in both the vein and aorta on tubings extruded at lower temperatures. The surface areas of renal infarction were smaller when lower temperature tubings were inserted into the aorta. Scanning electron microscopy showed that lower extrusion temperatures caused greater roughness on the tubings. This greater roughness was confirmed by roughness measurements. It is suggested that the association which has been demonstrated between roughness and thrombus formation might be due to the degree of adhesion of the thrombus to the surface rather than to differences in thrombogenicity.
对从一批聚氯乙烯树脂在110至205摄氏度的五个温度下挤出的管材，在绵羊的隐静脉和主动脉中进行了血栓形成性测试。在较低温度下挤出的管材的静脉和主动脉中都有更多血栓。当将较低温度的管材插入主动脉时，肾梗死的表面积较小。扫描电子显微镜显示，较低的挤出温度会使管材表面更粗糙。粗糙度测量证实了这种更大的粗糙度。有人提出，已证明的粗糙度与血栓形成之间的关联可能是由于血栓与表面的粘附程度，而不是血栓形成性的差异。
