Pinchuk L, Eckstein E C
J Biomed Mater Res. 1981 Mar;15(2):183-9. doi: 10.1002/jbm.820150206.
Homopolymers of the hydrogel poly(2-hydroxyethyl methacrylate) are produced with no observable bubbles trapped in the lattice by performing the free radical initiated polymerization reaction under pressure (700 kPa). Implantable hydrogel structures of intricate and exact geometry, such as nipples for ureteral anastomoses in the prosthetic urinary bladder, can be made using this technique.
通过在压力（700千帕）下进行自由基引发的聚合反应，制备出的水凝胶聚甲基丙烯酸2-羟乙酯的均聚物中没有观察到被困在晶格中的气泡。利用该技术可以制造出具有复杂精确几何形状的可植入水凝胶结构，如用于人工膀胱输尿管吻合术的乳头。
