Siwińska-Gołebiowska H, Borysewicz G
Probl Med Wieku Rozwoj. 1981;10:31-8.
In the Institute of Mother and Child in Warsaw there were determined normal values of IgG, IgA, IgM and IgE for different ages of children and youth. The determination of normal IgD levels is the last stage in this kind of studies concerning immunoglobulins. IgD levels were estimated in 372 cases in 19 age groups: in the cord sera, infant sera and older healthy children as well as in healthy adults sera. The IgD concentration was determined by Mancini method and given in I.U/ml. The results were statistically analysed. In all samples of cord sera no IgD traces were found. In infant sera (up to one year) IgD level is very low and was detected in 27% of cases. The percentage of detectability as well as the mean IgD concentration in serum grows systematically to the age of 15 years. There is high statistically significant correlation between serum IgD concentration and the age both for the arithmetical means (r = 0,33) and for geometrical values (r = 0,39). The correlation coefficients between detectability of serum IgD and age are higher (linear dependence-r = 0,67, square dependence - r = 0,75).
在华沙母婴研究所测定了不同年龄段儿童和青少年的IgG、IgA、IgM和IgE的正常值。确定正常IgD水平是这类免疫球蛋白研究的最后阶段。对19个年龄组的372例进行了IgD水平评估：脐血血清、婴儿血清、大龄健康儿童以及健康成人血清。采用曼西尼法测定IgD浓度，结果以国际单位/毫升表示。对结果进行了统计学分析。在所有脐血血清样本中均未发现IgD痕迹。在婴儿血清（1岁以内）中，IgD水平非常低，仅在27%的病例中检测到。血清中IgD的可检测百分比以及平均浓度随年龄增长至15岁呈系统性升高。血清IgD浓度与年龄之间在算术平均值（r = 0.33）和几何值（r = 0.39）方面均存在高度统计学显著相关性。血清IgD可检测性与年龄之间的相关系数更高（线性相关性 - r = 0.67，平方相关性 - r = 0.75）。
