Immunoglobulin D in childhood. I. Serum level in healthy children.

The IgD content in cord blood was determined in 83 newborns and 203 healthy children of 2 weeks to 16 years. IgD was present only in 2 among 83 tested newborns. The IgD concentration in sera of their mothers was higher than the average IgD concentration in pregnant women. Statistical analysis of data from 203 healthy children showed, that the IgD concentration increases to the age 8-12 years, and then it decreases. In each of the age intervals investigated some percentage of children with undetectable IgD was found. This percentage decreases with age. No significant differences were found in serum concentration of IgD depending on sex of the tested children.