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患有 A 类免疫球蛋白异常或免疫球蛋白低下血症的儿童血清中 IgD 的浓度。

The concentration of IgD in blood sera of children suffering from dys- or hypogammaglobulinaemia of class A.

作者信息

Jankowski A, Ziemiańska E, Kowalik W

出版信息

Arch Immunol Ther Exp (Warsz). 1987;35(1):43-7.

PMID:3498462
Abstract

6580 children inhabitans of selected region of Lower Silesia and 475 children with recurrent respiratory tract infections as well as 65 children with chronic active hepatitis were tested. IgA level was determined in each case. In the cases where IgA was absent or a low level of this immunoglobulin was found (0.2 g/l) IgD concentration was determined. It was established that the frequency of dysgammaglobulinaemia of class A was 1/731 tested cases in the tested population and 1/119 cases in children with respiratory tract infections and 1/65 tested children with chronic active hepatitis. Hypogammaglobulinaemia of class A was found in 1/365 cases in the tested population and 1/20 cases in children with respiratory tract infections and 2/65 children with chronic aggressive hepatitis. In children with dysgammaglobulinaemia of class A lack of IgD in serum was found in 44% of the cases--however, in hypogammaglobulinaemia IgA lack of IgD in serum was found in 38% of the cases.

摘要

对下西里西亚选定地区的6580名儿童居民、475名患有反复呼吸道感染的儿童以及65名患有慢性活动性肝炎的儿童进行了检测。在每种情况下都测定了IgA水平。在IgA缺失或发现该免疫球蛋白水平较低(0.2 g/l)的情况下,测定了IgD浓度。结果确定,在受测人群中,A类γ球蛋白异常血症的发生率为1/731例受测病例,在患有呼吸道感染的儿童中为1/119例,在受测的患有慢性活动性肝炎的儿童中为1/65例。在受测人群中,A类低γ球蛋白血症的发生率为1/365例,在患有呼吸道感染的儿童中为1/20例,在患有慢性侵袭性肝炎的儿童中为2/65例。在患有A类γ球蛋白异常血症的儿童中,44%的病例血清中缺乏IgD——然而,在低γ球蛋白血症中,38%的病例血清中缺乏IgA和IgD。

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Arch Immunol Ther Exp (Warsz). 1987;35(1):43-7.
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