惠普尔病中的肌病
Myopathy in Whipple's disease.
作者信息
Swash M, Schwartz M S, Vandenburg M J, Pollock D J
出版信息
Gut. 1977 Oct;18(10):800-4. doi: 10.1136/gut.18.10.800.
Abstract
We report a patient with Whipple's disease who developed a myopathy that improved during antibiotic therapy. The muscle biopsy showed mild type 2 fibre atrophy, type 1 fibre preponderance, variability in fibre size, and changes in the myofibrillar pattern of affected fibres. Interfascicular macrophages contained PAS-positive material. With the electron microscope these macrophages contained membranous inclusions and bacillary bodies, similar to those seen in the jejunal biopsy.
摘要
我们报告了一名患有惠普尔病的患者，该患者出现了一种肌病，在抗生素治疗期间病情有所改善。肌肉活检显示轻度2型纤维萎缩、1型纤维优势、纤维大小变异以及受影响纤维的肌原纤维模式改变。束间巨噬细胞含有PAS阳性物质。在电子显微镜下，这些巨噬细胞含有膜状包涵体和杆菌样小体，类似于在空肠活检中所见。
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