Grgicević D, Pende B
Bilt Hematol Transfuz. 1981;9(1-3):77-88.
Effects of long term plasmapheresis on blood constituents was examined in the plasma donors from whom 220-660 ml of plasma was withdrawn weakly. The donors were submitted 3-300 times to double plasmapheresis procedures. Small decreases in concentrations of total proteins, albumins, gamma-globulins, immunoglobulins IgA and IgM were observed as well as the increases in the concentrations of alpha-1-globulins (p less than 0,05), alpha-2-globulins (p less than 0,05), beta-globulins (p less than 0,05) and immunoglobulins IgG (p less than 0,05). The statistically significant changes were observed earlier in the course of plasmapheresis in donors submitted to more intensive regime.
对长期进行血浆置换的献血者血液成分的影响进行了研究，这些献血者每次少量抽取220 - 660毫升血浆。这些献血者接受了3 - 300次双份血浆置换程序。观察到总蛋白、白蛋白、γ-球蛋白、免疫球蛋白IgA和IgM浓度略有下降，同时α-1球蛋白（p < 0.05）、α-2球蛋白（p < 0.05）、β-球蛋白（p < 0.05）和免疫球蛋白IgG（p < 0.05）浓度有所升高。在接受更密集方案的献血者中，血浆置换过程中更早观察到统计学上的显著变化。
