Levamisole and leucocyte migration into sponge exudates.

Locally administered levamisole enhanced leucocyte migration into inert sponges implanted into rats for either 4 or 48 h. The stimulated cell at both times was predominantly the polymorphonuclear neutrophil. Locally administered levamisole also enhanced leucocyte migration into inert sponges implanted into arthritic rats, during the primary stage as well as well as during the secondary stage after adjuvant injection when arthritis had been fully established.