Greig P D, Langer B, Blendis L M, Taylor B R, Glynn M F
Am J Surg. 1980 Jan;139(1):125-31. doi: 10.1016/0002-9610(80)90241-x.
The results and complications in our first 23 consecutive patients receiving the peritoneovenous shunt for intractiable hepatic ascites are presented. A good initial diuretic effect was obtained in 20 of the 23 patients, with reversal of hepatorenal failure in 3 of 5 patients. The postoperative complication rate was high (74 percent). Infection, coagulopathy and complication of the underlying liver disease contributed to a mortality rate of 26 percent. Late complications were related to the primary liver disease. The 6 month survival rate was 58 percent and the 1 hear survival rate 52 percent with five patients followed up for more than 2 years. Because of the significant morbidity and mortality associated with the peritoneovenous shunt, we recommend it only for patients with massive intractable hepatic ascites whose condition is refractory to maximal medical therapy.
本文介绍了连续23例接受腹腔静脉分流术治疗顽固性肝腹水患者的治疗结果及并发症情况。23例患者中有20例最初获得了良好的利尿效果,5例肝肾衰竭患者中有3例病情逆转。术后并发症发生率较高(74%)。感染、凝血功能障碍及潜在肝脏疾病并发症导致死亡率达26%。晚期并发症与原发性肝脏疾病有关。6个月生存率为58%,1年生存率为52%,5例患者随访时间超过2年。由于腹腔静脉分流术存在显著的发病率和死亡率,我们建议仅用于经最大程度药物治疗仍难以控制病情的大量顽固性肝腹水患者。