Strohl K P, Feldman N T, Saunders N A, O'Connor N
J Trauma. 1980 Jan;20(1):78-80.
In victims of carbon monoxide (CO) poisoning, metabolic acidosis has been considered a clinical finding of ominous prognostic importance. In previous studies, such patients either died or suffered serious neurologic sequelae, resulting in the recommendation by some authors that these patients require more complicated therapy, including hyperbaric oxygen and hypothermia. This report documents the full neurologic recovery of three patients with severe metabolic acidosis and CO poisoning. Our experience indicates that acidosis may not be as important a prognostic factor as previously thought, and that randomized prospective trials are needed in such patients before more complicated therapy becomes accepted medical practice.
在一氧化碳（CO）中毒患者中，代谢性酸中毒一直被视为具有不祥预后意义的临床发现。在以往的研究中，这类患者要么死亡，要么遭受严重的神经后遗症，因此一些作者建议这些患者需要更复杂的治疗，包括高压氧和低温治疗。本报告记录了3例严重代谢性酸中毒合并CO中毒患者的完全神经功能恢复情况。我们的经验表明，酸中毒可能不像以前认为的那样是一个重要的预后因素，在更复杂的治疗成为公认的医学实践之前，需要对这类患者进行随机前瞻性试验。
