Dolan M C
CMAJ. 1985 Sep 1;133(5):392-9.
Carbon monoxide poisoning is a significant cause of illness and death. Its protean symptoms probably lead to a gross underestimation of its true incidence. Low levels of carbon monoxide aggravate chronic cardiopulmonary problems, and high levels are associated with cardiac arrhythmias and cerebral edema. Patients who survive acute poisoning are at risk of delayed neurologic sequelae. The measurement of carboxyhemoglobin levels does not reveal the tissue levels of carbon monoxide but is useful in determining therapy. Treatment includes the monitoring and management of cardiac arrhythmias and oxygenation. Hyperbaric oxygenation is beneficial, but there are currently no definite criteria for its use.
一氧化碳中毒是疾病和死亡的一个重要原因。其多样的症状可能导致对其真实发病率的严重低估。低水平的一氧化碳会加重慢性心肺问题,而高水平的一氧化碳则与心律失常和脑水肿相关。急性中毒幸存者有发生迟发性神经后遗症的风险。碳氧血红蛋白水平的测定并不能反映一氧化碳的组织水平,但有助于确定治疗方案。治疗包括对心律失常和氧合的监测与管理。高压氧治疗有益,但目前尚无明确的使用标准。