Young D C, Popat R, Luther E R, Scott K E, Writer W D
Am J Obstet Gynecol. 1980 Feb 1;136(3):321-4. doi: 10.1016/0002-9378(80)90856-x.
Thirty-two healthy pregnant women at term who were to undergo cesarean section following epidural anesthesia were randomly assigned to receive preoperatively, by face mask, room air or oxygen for more than 10 minutes. Patients were kept at a left lateral tilt position of 15 degrees and were unaware which gas was administered. Oxygenation significantly increased (p less than 0.05) maternal PO2 to 283 mm Hg (SD 67). The cord vein PO2 of the group receiving oxygen was 34 mm Hg (SD 6), significantly higher (p less than 0.01) than the value of 26 mm Hg (SD 7) in the group receiving room air. The cord artery PO2 of the oxygen group was also significantly higher (p less than 0.05) at 20 mm Hg (SD 6) versus 15 mm Hg (SD 6). No other cord gas values were significantly different. There was no significant difference in the cord vein-artery PO2 differential. There was no significant difference in the infants' hematocrits determined at 4 hours of age in the two groups. All infants were in excellent condition (1-minute Apgar score greater than or equal to 8).
32名足月健康孕妇，拟在硬膜外麻醉下行剖宫产术，随机分为两组，术前通过面罩分别给予室内空气或氧气10分钟以上。患者保持15度左侧卧位，且不知道给予的是哪种气体。氧合作用显著提高（p<0.05），母体动脉血氧分压（PO2）升至283 mmHg（标准差67）。吸氧组的脐静脉PO2为34 mmHg（标准差6），显著高于（p<0.01）吸室内空气组的26 mmHg（标准差7）。吸氧组的脐动脉PO2也显著更高（p<0.05），为20 mmHg（标准差6），而吸室内空气组为15 mmHg（标准差6）。其他脐血气体值无显著差异。脐静脉-动脉PO2差值无显著差异。两组婴儿出生4小时时测定的血细胞比容无显著差异。所有婴儿状况良好（1分钟阿氏评分大于或等于8分）。
