Acute asthma: the use of subcutaneous epinephrine in therapy.

The effects of three dosages of epinephrine given one to three times were investigated in acute asthma. Variable changes occurred in arterial blood gases and, except for the 0.1 mg dose, statistically significant increases in mean PEFR after a single injection. Repeated administration of 0.1 mg was, however, an effective bronchodilator regimen.