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从莫里斯5123tc肝癌中纯化一种独特的钙结合蛋白。

The purification of a unique calcium-binding protein from Morris hepatoma 5123 tc.

作者信息

MacManus J P

出版信息

Biochim Biophys Acta. 1980 Feb 27;621(2):296-304. doi: 10.1016/0005-2795(80)90181-6.

Abstract

A heat-stable Ca2+-binding protein was purified to homogeneity from Morris hepatoma 5123 tc. It had an apparent molecular weight of 11 000, and isoelectric point of 3.9, and bound two atoms of calcium per molecule of protein. The spectral and amino acid analysis indicated the tumour protein to be similar to the parvalbumins. This protein has been shown to be absent in liver.

摘要

从莫里斯肝癌5123 tc中纯化出一种热稳定的钙结合蛋白,达到了同质纯。它的表观分子量为11000,等电点为3.9,每分子蛋白质结合两个钙原子。光谱和氨基酸分析表明,该肿瘤蛋白与小白蛋白相似。已证明这种蛋白在肝脏中不存在。

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