骨髓瘤中的淀粉样关节病——滑膜细胞质内沉积

Amyloid arthropathy in myelomatosis--intracytoplasmic synovial deposition.

作者信息

French B T

出版信息

Histopathology. 1980 Jan;4(1):21-8. doi: 10.1111/j.1365-2559.1980.tb02894.x.

DOI:10.1111/j.1365-2559.1980.tb02894.x

Abstract

An unusual case is described of a West Indian man who presented with symptoms of an acute polyarthritis and who was found to have myelomatosis. At necropsy, generalized amyloidosis was found with particular involvement of synovial tissue. Myelomatosis presenting as an acute polyarthritis resembling rheumatoid arthritis is an uncommon, although well recognized entity, whereas an arthritic picture produced by amyloidosis is exceptional. The occurrence of joint pathology in myelomatosis and amyloidosis is discussed and the unique feature of intracytoplasmic amyloid deposition seen in this case is stressed.

摘要

本文描述了一例不寻常的病例，一名西印度男子出现急性多关节炎症状，经检查发现患有骨髓瘤病。尸检时发现全身淀粉样变性，滑膜组织尤其受累。骨髓瘤病表现为类似类风湿关节炎的急性多关节炎虽已得到公认，但并不常见，而由淀粉样变性引起的关节炎表现则极为罕见。本文讨论了骨髓瘤病和淀粉样变性中关节病理的发生情况，并强调了该病例中所见的胞浆内淀粉样沉积的独特特征。

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