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骨髓瘤中的淀粉样关节病——滑膜细胞质内沉积

Amyloid arthropathy in myelomatosis--intracytoplasmic synovial deposition.

作者信息

French B T

出版信息

Histopathology. 1980 Jan;4(1):21-8. doi: 10.1111/j.1365-2559.1980.tb02894.x.

DOI:10.1111/j.1365-2559.1980.tb02894.x
PMID:7353815
Abstract

An unusual case is described of a West Indian man who presented with symptoms of an acute polyarthritis and who was found to have myelomatosis. At necropsy, generalized amyloidosis was found with particular involvement of synovial tissue. Myelomatosis presenting as an acute polyarthritis resembling rheumatoid arthritis is an uncommon, although well recognized entity, whereas an arthritic picture produced by amyloidosis is exceptional. The occurrence of joint pathology in myelomatosis and amyloidosis is discussed and the unique feature of intracytoplasmic amyloid deposition seen in this case is stressed.

摘要

本文描述了一例不寻常的病例,一名西印度男子出现急性多关节炎症状,经检查发现患有骨髓瘤病。尸检时发现全身淀粉样变性,滑膜组织尤其受累。骨髓瘤病表现为类似类风湿关节炎的急性多关节炎虽已得到公认,但并不常见,而由淀粉样变性引起的关节炎表现则极为罕见。本文讨论了骨髓瘤病和淀粉样变性中关节病理的发生情况,并强调了该病例中所见的胞浆内淀粉样沉积的独特特征。

相似文献

1
Amyloid arthropathy in myelomatosis--intracytoplasmic synovial deposition.骨髓瘤中的淀粉样关节病——滑膜细胞质内沉积
Histopathology. 1980 Jan;4(1):21-8. doi: 10.1111/j.1365-2559.1980.tb02894.x.
2
Multiple myeloma with synovial amyloid deposition.伴有滑膜淀粉样沉积的多发性骨髓瘤。
Rheumatol Phys Med. 1972 Aug;11(7):349-53. doi: 10.1093/rheumatology/11.7.349.
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Amyloid arthropathy associated with multiple myeloma: a systematic analysis of 101 reported cases.与多发性骨髓瘤相关的淀粉样变关节病:101 例报告病例的系统分析。
Semin Arthritis Rheum. 2013 Dec;43(3):405-12. doi: 10.1016/j.semarthrit.2013.07.004. Epub 2013 Aug 28.
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A study of amyloid arthropathy in multiple myeloma.多发性骨髓瘤中淀粉样变关节病的一项研究。
Q J Med. 1981 Autumn;50(200):417-33.
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Amyloid arthropathy in a patient with psoriasis and amyloidosis.一名银屑病和淀粉样变性患者的淀粉样关节病。
Arthritis Rheum. 1981 Oct;24(10):1320-3. doi: 10.1002/art.1780241014.
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[Amyloid arthropathy. An unusual complication of myelomatosis].[淀粉样变关节病。骨髓瘤的一种罕见并发症]
Ugeskr Laeger. 1971 Sep 10;133(36):1777-9.
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[Amyloidosis in plasmacytic myeloma with dominant manifestations of joint involvement].
Cas Lek Cesk. 1989 May 5;128(19):599-601.
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[Amyloid arthropathy and Bence Jones myeloma].[淀粉样关节病与本斯·琼斯骨髓瘤]
Med Clin (Barc). 1983 Jul 16;81(5):212-5.
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IgD myeloma with amyloid arthropathy.伴有淀粉样变关节病的IgD型骨髓瘤
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Amyloid arthropathy and Waldenström macroglobulinemia.
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引用本文的文献

1
Amyloid in osteoarthritic hip joints: deposits in relation to chondromatosis, pyrophosphate, and inflammatory cell infiltrate in the synovial membrane and fibrous capsule.
Ann Rheum Dis. 1983 Dec;42(6):659-64. doi: 10.1136/ard.42.6.659.
2
Clinicopathological importance of deposits of amyloid in the femoral head.股骨头中淀粉样蛋白沉积的临床病理重要性。
J Clin Pathol. 1985 Aug;38(8):868-72. doi: 10.1136/jcp.38.8.868.
3
Amyloid in intervertebral discs: a histopathological investigation of surgical material from 100 consecutive operations on herniated discs.椎间盘内的淀粉样蛋白:对100例连续椎间盘突出症手术材料的组织病理学研究
Ann Rheum Dis. 1986 Mar;45(3):239-43. doi: 10.1136/ard.45.3.239.
4
Amyloid deposits in the knee joint at autopsy.尸检时膝关节出现淀粉样沉积物。
Ann Rheum Dis. 1986 Aug;45(8):668-72. doi: 10.1136/ard.45.8.668.
5
Role of amyloid in dialysis-related arthropathies. A morphological analysis of 23 cases.
Virchows Arch A Pathol Anat Histopathol. 1990;417(6):523-8. doi: 10.1007/BF01625733.