Cary N R
J Clin Pathol. 1985 Aug;38(8):868-72. doi: 10.1136/jcp.38.8.868.
The pattern of amyloid deposits in the femoral head is described in four cases, two of which had deposits of amyloid related to age and two of which had generalised systemic amyloidosis (one of primary amyloidosis, one of multiple myeloma). The deposition of amyloid in the articular cartilage of the femoral head was similar in all four cases. Heavy deposits of synovial amyloid were identified in the case with primary amyloidosis and in one of the cases with amyloidosis related to age. Both cases of generalised systemic amyloidosis showed abundant deposits of amyloid in the bone marrow. Amyloid was not present in the bone marrow of either case with amyloidosis related to age. The importance of these findings is discussed in relation to the pathogenesis of the arthropathy syndrome of a rheumatoid type described in cases of primary amyloidosis and multiple myeloma.
描述了4例股骨头淀粉样沉积物的模式，其中2例有与年龄相关的淀粉样沉积，2例有全身性淀粉样变性（1例为原发性淀粉样变性，1例为多发性骨髓瘤）。4例中股骨头关节软骨的淀粉样沉积相似。在原发性淀粉样变性病例和1例与年龄相关的淀粉样变性病例中发现了大量滑膜淀粉样沉积。2例全身性淀粉样变性病例的骨髓中均显示有大量淀粉样沉积。2例与年龄相关的淀粉样变性病例的骨髓中均未发现淀粉样物质。结合原发性淀粉样变性和多发性骨髓瘤病例中描述的类风湿样关节病综合征的发病机制，讨论了这些发现的重要性。
