Salisbury R E, Bevin A G, Steinkraus G E, Enterline D S
J Trauma. 1980 Feb;20(2):120-2.
Using a standardized laboratory rat model of burn wound sepsis, a regimen of once a day application of Silvadene has been found to be more effective treatment than Sulfamylon or cerium-Silvadene. Delaying treatment following infection resulted in decreased survival. Possible reasons for difference in mortality are once-daily application, or perhaps a change in sensitivity between drugs and the infective organism (Ps. aeruginosa) over time.
使用标准化的烧伤创面脓毒症实验大鼠模型，已发现每日一次应用磺胺嘧啶银的治疗方案比甲磺灭脓或铈 - 磺胺嘧啶银更有效。感染后延迟治疗会导致存活率降低。死亡率存在差异的可能原因是每日一次的应用，或者可能是随着时间推移药物与感染生物体（铜绿假单胞菌）之间的敏感性发生了变化。
