破骨细胞源自造血干细胞。
Osteoclasts derived from haematopoietic stem cells.
作者信息
Ash P, Loutit J F, Townsend K M
出版信息
Nature. 1980 Feb 14;283(5748):669-70. doi: 10.1038/283669a0.
DOI:10.1038/283669a0
PMID:7354855
Abstract
The origins of the multinucleated osteoclast have been controversial, with osteogenic precursors and haematopoietic stem cells as candidates. Recent evidence for the latter is persuasive but circumstantial. We report here direct evidence obtained in radiation chimaeras from a natural cytoplasmic cell marker transmitted by the donated haematopoietic stem cell.
摘要
多核破骨细胞的起源一直存在争议，成骨前体细胞和造血干细胞都被视为候选来源。近期关于后者的证据虽有说服力，但属于间接证据。我们在此报告通过辐射嵌合体从捐赠的造血干细胞传递的一种天然细胞质细胞标记物中获得的直接证据。
Zotero 插件