流感病毒的温度敏感突变体。乌栋ts-1A2供体病毒中两个温度敏感损伤位点的鉴定以及这两个温度敏感损伤的存在与可预测的减毒水平的相关性。 - Suppr

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超能文献

Temperature-sensitive mutants of influenza virus. Identification of the loci of the two ts lesions in the Udorn-ts-1A2 donor virus and the correlation of the presence of these two ts lesions with a predictable level of attenuation.

作者信息

Massicot J G, Murphy B R, Thierry F, Markoff L, Huang K Y, Chanock R M

出版信息

Virology. 1980 Feb;101(1):242-9. doi: 10.1016/0042-6822(80)90499-7.

DOI:10.1016/0042-6822(80)90499-7

PMID:7355577

Abstract

摘要

相似文献

Temperature-sensitive mutants of influenza virus. Identification of the loci of the two ts lesions in the Udorn-ts-1A2 donor virus and the correlation of the presence of these two ts lesions with a predictable level of attenuation.流感病毒的温度敏感突变体。乌栋ts-1A2供体病毒中两个温度敏感损伤位点的鉴定以及这两个温度敏感损伤的存在与可预测的减毒水平的相关性。

Virology. 1980 Feb;101(1):242-9. doi: 10.1016/0042-6822(80)90499-7.

Temperature-sensitive mutants of influenza A virus. Transfer of the two ts-1A2 ts lesions present in the Udorn/72-ts-1A2 donor virus to the influenza A/Alaska/6/77 (H3N2) wild type virus.甲型流感病毒的温度敏感突变体。将存在于乌栋/72-ts-1A2供体病毒中的两个ts-1A2 ts损伤转移至甲型流感病毒/阿拉斯加/6/77（H3N2）野生型病毒。

Arch Virol. 1980;65(2):175-86. doi: 10.1007/BF01317329.

Temperature-sensitive mutants of influenza virus. XVI. Transfer of the two ts lesions present in the Udorn/72-ts-1A2 donor virus to the Victoria/3/75 wild-type virus.流感病毒的温度敏感突变体。十六。将乌东/72-ts-1A2供体病毒中存在的两个温度敏感损伤转移至维多利亚/3/75野生型病毒。

Virology. 1978 Jul 15;88(2):244-51. doi: 10.1016/0042-6822(78)90281-7.

Temperature-sensitive mutants of influenza A virus: transfer of the two temperature-sensitive lesions in the Udorn/72-ts-1A2 virus to the A2Hong Kong/123/77 (H1N1) wild-type virus.甲型流感病毒的温度敏感突变体：将乌东/72-ts-1A2病毒中的两个温度敏感损伤转移至A2香港/123/77（H1N1）野生型病毒。

Infect Immun. 1980 Jun;28(3):792-8. doi: 10.1128/iai.28.3.792-798.1980.

Production and level of genetic stability of an influenza A virus temperature-sensitive mutant containing two genes with ts mutations.一种含有两个带有温度敏感（ts）突变基因的甲型流感病毒温度敏感突变株的产生及其遗传稳定性水平

Infect Immun. 1982 Jul;37(1):235-42. doi: 10.1128/iai.37.1.235-242.1982.

Temperature-sensitive mutants of influenza A/Udorn/72 (H3N2) virus. III. Genetic analysis of temperature-dependent host range mutants.甲型流感病毒A/Udorn/72（H3N2）的温度敏感突变体。III. 温度依赖性宿主范围突变体的遗传分析

Virology. 1983 Jan 15;124(1):35-44. doi: 10.1016/0042-6822(83)90288-x.

Temperature-sensitive mutants of influenza virus. XV. The genetic and biological characterization of a recombinant influenza virus containing two ts lesions produced by mating two complementing, single lesion ts mutants.流感病毒的温度敏感突变体。十五、一种重组流感病毒的遗传和生物学特性，该重组病毒含有通过将两个互补的单损伤温度敏感突变体杂交产生的两个温度敏感损伤。

Virology. 1978 Jul 15;88(2):231-43. doi: 10.1016/0042-6822(78)90280-5.

Evaluation of a phenotypic revertant of the A/Alaska/77-ts-1A2 reassortant virus in hamsters and in seronegative adult volunteers: further evidence that the temperature-sensitive phenotype is responsible for attenuation of ts-1A2 reassortant viruses.对A/阿拉斯加/77-ts-1A2重配病毒在仓鼠和血清阴性成年志愿者中的表型回复突变体的评估：温度敏感表型导致ts-1A2重配病毒减毒的进一步证据。

Infect Immun. 1982 May;36(2):645-50. doi: 10.1128/iai.36.2.645-650.1982.

Localization of the Ts defect in two Ts mutants of influenza A virus: evidence for the occurrence of intracistronic complementation between Ts mutants of influenza A virus coding for the neuraminidase and nucleoprotein polypeptides.甲型流感病毒两个温度敏感（Ts）突变体中Ts缺陷的定位：编码神经氨酸酶和核蛋白多肽的甲型流感病毒Ts突变体之间发生顺反子内互补的证据。

Virology. 1980 Mar;101(2):484-92. doi: 10.1016/0042-6822(80)90462-6.

Localization of the ts defects of ts mutants of influenza A virus using complementation analysis and gel analysis of the RNA segments of recombinants.利用重组体RNA片段的互补分析和凝胶分析对甲型流感病毒ts突变体的ts缺陷进行定位

Virology. 1981 Nov;115(1):137-48. doi: 10.1016/0042-6822(81)90096-9.

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The amantadine-sensitivity of recombinant and parental influenza virus strains.重组流感病毒株和亲本流感病毒株的金刚烷胺敏感性

Med Microbiol Immunol. 1981;169(4):259-68. doi: 10.1007/BF02125525.

Characterization of the temperature sensitive phenotype of the A/Ann Arbor/6/60 cold-adapted virus and its recombinants.A/安阿伯/6/60冷适应病毒及其重组体温度敏感表型的特征分析。

Infect Immun. 1981 May;32(2):960-3. doi: 10.1128/iai.32.2.960-963.1981.

Hemagglutinin-specific enzyme-linked immunosorbent assay for antibodies to influenza A and B viruses.用于检测甲型和乙型流感病毒抗体的血凝素特异性酶联免疫吸附测定

J Clin Microbiol. 1981 Mar;13(3):554-60. doi: 10.1128/jcm.13.3.554-560.1981.

Evaluation of influenza A/Hong Kong/123/77 (H1N1) ts-1A2 and cold-adapted recombinant viruses in seronegative adult volunteers.甲型流感病毒/香港/123/77（H1N1）ts-1A2及冷适应重组病毒在血清阴性成年志愿者中的评估。

Infect Immun. 1980 Aug;29(2):348-55. doi: 10.1128/iai.29.2.348-355.1980.

Infect Immun. 1982 Jul;37(1):235-42. doi: 10.1128/iai.37.1.235-242.1982.

Use of specific single stranded DNA probes cloned in M13 to study the RNA synthesis of four temperature-sensitive mutants of HK/68 influenza virus.使用克隆于M13的特异性单链DNA探针研究HK/68流感病毒四个温度敏感突变株的RNA合成。

Nucleic Acids Res. 1982 May 11;10(9):2925-38. doi: 10.1093/nar/10.9.2925.

Nucleoprotein and membrane protein genes are associated with restriction of replication of influenza A/Mallard/NY/78 virus and its reassortants in squirrel monkey respiratory tract.核蛋白基因和膜蛋白基因与甲型/绿头鸭/纽约/78病毒及其重配病毒在松鼠猴呼吸道中的复制受限有关。

J Virol. 1985 Mar;53(3):771-5. doi: 10.1128/JVI.53.3.771-775.1985.

Characterization of a gene coding for M proteins which is involved in host range restriction of an avian influenza A virus in monkeys.一种编码M蛋白的基因的特性，该基因与甲型禽流感病毒在猴子中的宿主范围限制有关。

J Virol. 1986 Feb;57(2):697-700. doi: 10.1128/JVI.57.2.697-700.1986.

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