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一种编码M蛋白的基因的特性,该基因与甲型禽流感病毒在猴子中的宿主范围限制有关。

Characterization of a gene coding for M proteins which is involved in host range restriction of an avian influenza A virus in monkeys.

作者信息

Buckler-White A J, Naeve C W, Murphy B R

出版信息

J Virol. 1986 Feb;57(2):697-700. doi: 10.1128/JVI.57.2.697-700.1986.

Abstract

The nucleotide sequence of the region of RNA segment 7 coding for the M1 and M2 proteins of avian influenza A/Mallard/New York/6750/78 was determined, and the deduced amino acid sequences were compared to other avian and human M protein sequences. The M2 proteins of the avian and human viruses have diverged much more than the M1 proteins, although amino acids specific for avian and human viruses were found in both M1 and M2 proteins.

摘要

测定了甲型禽流感病毒A/野鸭/纽约/6750/78株RNA片段7中编码M1和M2蛋白区域的核苷酸序列,并将推导的氨基酸序列与其他禽源和人源M蛋白序列进行了比较。尽管在M1和M2蛋白中均发现了禽源和人源病毒特有的氨基酸,但禽源病毒和人源病毒的M2蛋白差异比M1蛋白大得多。

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本文引用的文献

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Nucleotide sequence of fowl plague virus RNA segment 7.禽瘟病毒RNA片段7的核苷酸序列。
J Gen Virol. 1982 Jan;58 Pt 1:211-5. doi: 10.1099/0022-1317-58-1-211.

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