Mintz G S, Kotler M N, Parry W R, Segal B L
Am J Cardiol. 1980 Feb;45(2):253-9. doi: 10.1016/0002-9149(80)90643-8.
Forty-five patients who had surgical therapy for pure mitral insufficiency were evaluated prospectively with both M mode and two dimensional echocardiography; 26 patients (Group I) had a flail mitral valve leaflet, and 19 patients (Group II) had intact chordae tendineae. The M mode echocardiographic criteria of a flail valve (systolic left atrial echoes, systolic mitral valve flutter, diastolic mitral flutter and chaotic paradoxic diastolic posterior leaflet motion) were compared statistically with the two dimensional echocardiographic criterion (loss of systolic leaflet coaptation). The presence of one M mode echocardiographic finding had a sensitivity of 60 percent, a specificity of 53 percent, a predictive accuracy of 63 percent and a predictive value of 50 percent. The sensitivity (96 percent), specificity (84 percent), predictive accuracy (89 percent) and predictive value (94 percent) of the two dimensional echocardiogram were statistically superior to those of the M mode study (p less than 0.05 or better for each criterion). Thus, two dimensional echocardiography is distinctly superior to M mode echocardiography in the diagnosis of flail mitral valve leaflets.
对45例因单纯二尖瓣关闭不全接受手术治疗的患者进行了M型和二维超声心动图的前瞻性评估；26例患者（第一组）有连枷样二尖瓣叶，19例患者（第二组）腱索完整。将连枷样瓣膜的M型超声心动图标准（收缩期左房回声、收缩期二尖瓣扑动、舒张期二尖瓣扑动和舒张期后叶反常混乱运动）与二维超声心动图标准（收缩期瓣叶对合丧失）进行统计学比较。一项M型超声心动图表现的敏感性为60%，特异性为53%，预测准确性为63%，预测值为50%。二维超声心动图的敏感性（96%）、特异性（84%）、预测准确性（89%）和预测值（94%）在统计学上优于M型检查（每项标准p<0.05或更佳）。因此，在诊断连枷样二尖瓣叶方面，二维超声心动图明显优于M型超声心动图。
