Himelman R B, Kusumoto F, Oken K, Lee E, Cahalan M K, Shah P M, Schiller N B
Department of Medicine, University of California, San Francisco 94133.
J Am Coll Cardiol. 1991 Jan;17(1):272-9. doi: 10.1016/0735-1097(91)90738-u.
To determine the echocardiographic and Doppler characteristics of mitral regurgitation associated with a flail mitral valve, precordial and transesophageal echocardiography with pulsed wave and Doppler color flow mapping was performed in 17 patients with a flail mitral valve leaflet due to ruptured chordae tendineae (Group I) and 22 patients with moderate or severe mitral regurgitation due to other causes (Group II). Echocardiograms were performed before or during cardiac surgery; cardiac catheterization was also performed in 28 patients (72%). Mitral valve disease was confirmed at cardiac surgery in all patients. By echocardiography, the presence of a flail mitral valve leaflet was defined by the presence of abnormal mitral leaflet coaptation or ruptured chordae. Using these criteria, transesophageal imaging showed a trend toward greater sensitivity and specificity than precordial imaging in the diagnosis of flail mitral valve leaflet. By Doppler color flow mapping, a flail mitral valve leaflet was also characterized by an eccentric, peripheral, circular mitral regurgitant jet that closely adhered to the walls of the left atrium. The direction of flow of the eccentric jet in the left atrium distinguished a flail anterior from a flail posterior leaflet. By transesophageal echocardiography with Doppler color flow mapping, the ratio of mitral regurgitant jet arc length to radius of curvature was significantly higher in Group I than Group II patients (5.0 +/- 2.3 versus 0.7 +/- 0.6, p less than 0.001); all of the Group I patients and none of the Group II patients had a ratio greater than 2.5.(ABSTRACT TRUNCATED AT 250 WORDS)
为确定连枷样二尖瓣所致二尖瓣反流的超声心动图和多普勒特征,对17例因腱索断裂导致连枷样二尖瓣叶的患者(I组)和22例因其他原因导致中重度二尖瓣反流的患者(II组)进行了胸前和经食管超声心动图检查,并采用脉冲波和多普勒彩色血流图。超声心动图检查在心脏手术前或手术中进行;28例患者(72%)还进行了心导管检查。所有患者均在心脏手术中确诊二尖瓣疾病。通过超声心动图,连枷样二尖瓣叶的存在通过二尖瓣叶异常对合或腱索断裂来定义。使用这些标准,经食管成像在诊断连枷样二尖瓣叶方面比胸前成像显示出更高的敏感性和特异性趋势。通过多普勒彩色血流图,连枷样二尖瓣叶还表现为偏心、周边、圆形的二尖瓣反流束,紧密附着于左心房壁。左心房内偏心反流束的血流方向可区分连枷样前叶和连枷样后叶。通过经食管超声心动图和多普勒彩色血流图检查,I组患者二尖瓣反流束弧长与曲率半径之比显著高于II组患者(5.0±2.3对0.7±0.6,p<0.001);I组所有患者及II组无患者该比值大于2.5。(摘要截于250字)