Papachristou D N, Agnanti N, Fortner J G
Am J Surg. 1980 Feb;139(2):193-6. doi: 10.1016/0002-9610(80)90252-4.
In a study comparing 1,496 gastric cancer patients with 1,496 matched control patients, gastrectomy or simple gastrojejunostomy for ulcer predisposed to gastric cancer whereas medical ulcer treatment did not. Gastric carcinomas after ulcer surgery appeared after age 50 years. The time interval between ulcer treatment and the appearance of gastric cancer gradually decreased as the patients' age approached 50 years. The selection of operated ulcer patients for gastroscopic evaluation should be based on age rather than sex, location of the ulcer, ulcer-cancer interval or type of ulcer operation. Gastroscopy was the most effective diagnostic tool in the management of such patients.
在一项对1496例胃癌患者和1496例匹配的对照患者进行比较的研究中，对于易患胃癌的溃疡，胃切除术或单纯胃空肠吻合术有效，而药物性溃疡治疗则无效。溃疡手术后的胃癌出现在50岁以后。随着患者年龄接近50岁，溃疡治疗与胃癌出现之间的时间间隔逐渐缩短。选择接受手术的溃疡患者进行胃镜评估应基于年龄，而非性别、溃疡位置、溃疡至癌症的间隔时间或溃疡手术类型。胃镜检查是管理此类患者最有效的诊断工具。
