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普萘洛尔过量

Propranolol overdose.

作者信息

Salzberg M R, Gallagher E J

出版信息

Ann Emerg Med. 1980 Jan;9(1):26-7. doi: 10.1016/s0196-0644(80)80436-7.

Abstract

This is a report of a patient who survived a large propranolol overdose, as documented by toxic blood levels. The signs and symptoms were those of profound inotropic and moderate chronotropic cardiotoxicity which failed to respond to parasympatholytics or catecholamines, but subsequently reversed coincident with the administration of glucagon. We report this case because of the sudden development of shock in a patient who looked deceptively well, and because of the improvement apparently brought about by glucagon.

摘要

这是一份关于一名患者的报告,该患者因血药浓度检测证实发生大剂量普萘洛尔过量中毒后存活。其体征和症状表现为严重的变力性和中度的变时性心脏毒性,对副交感神经阻滞剂或儿茶酚胺均无反应,但随后在使用胰高血糖素后症状得到缓解。我们报告此病例是因为该患者看似情况良好却突然发生休克,以及胰高血糖素明显带来了病情改善。

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