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胰高血糖素在钙通道阻滞剂过量病例中的应用。

The use of glucagon in a case of calcium channel blocker overdose.

作者信息

Doyon S, Roberts J R

机构信息

Department of Emergency Medicine, Mercy Catholic Medical Center, Philadelphia.

出版信息

Ann Emerg Med. 1993 Jul;22(7):1229-33. doi: 10.1016/s0196-0644(05)80997-7.

Abstract

The hypotension and myocardial depression that result from calcium channel blocker ingestion often are refractory to standard therapeutic modalities. Anecdotal reports on the use of glucagon have failed to show significant hemodynamic improvement. We report the first case of calcium channel blocker overdose that responded to glucagon. We conclude that glucagon is safe and effective in the management of hemodynamic instability associated with calcium channel blocker poisonings.

摘要

钙通道阻滞剂摄入所致的低血压和心肌抑制通常对标准治疗方式无效。关于使用胰高血糖素的轶事报道未能显示出显著的血流动力学改善。我们报告了首例对胰高血糖素产生反应的钙通道阻滞剂过量病例。我们得出结论,胰高血糖素在治疗与钙通道阻滞剂中毒相关的血流动力学不稳定方面是安全有效的。

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