Hawkins D B, Demeter M J, Barnett T E
Laryngoscope. 1980 Jan;90(1):98-109. doi: 10.1288/00005537-198001000-00012.
Two hundred fourteen patients admitted with a history of caustic ingestion are reviewed. Sixty-five had mucosal penetrating burns. Children five years of age and under accounted for 39% of admissions, but only 8% of burns requiring treatment. Adults accounted for 48% of admissions and 81% of burns requiring treatment. Complications associated with mucosal penetrating burns occurred in 31 patients; all but one were due to lye or acids. A three year prospective study evaluating methylprednisolone in the management of caustic burns is reported. This included 24 patients with mucosal penetrating burns due to lye or acids. The results of this study, and this review as a whole, indicate that methylprednisolone is beneficial in moderately severe burns due to lye, but is not indicated for severe burns from liquid lye, or for acid burns.
回顾了214例有腐蚀性物质摄入史的入院患者。65例有黏膜穿透性烧伤。5岁及以下儿童占入院人数的39%，但仅占需要治疗的烧伤患者的8%。成人占入院人数的48%，占需要治疗的烧伤患者的81%。31例患者发生了与黏膜穿透性烧伤相关的并发症；除1例外，均由碱液或酸液所致。报告了一项为期三年的前瞻性研究，评估甲基强的松龙在腐蚀性烧伤治疗中的作用。该研究包括24例因碱液或酸液导致黏膜穿透性烧伤的患者。这项研究的结果以及整个综述表明，甲基强的松龙对中度严重的碱液烧伤有益，但不适用于液态碱液所致的严重烧伤或酸液烧伤。
