葡聚糖凝胶球的伴刀豆球蛋白A凝集性。细胞凝集的物理模型。

Concanavalin A agglutinability of dextran gel spheres. A physical model for cells agglutination.

作者信息

Wang P Y, Evans D W, Zingg W

出版信息

Biochim Biophys Acta. 1980 Mar 3;628(2):228-39. doi: 10.1016/0304-4165(80)90370-0.

Abstract

Dextran is a polysaccharide which can interact with concanavalin A, and insolubilized dextran spheres are available with different degrees of swelling in water. One grade of these dextran gel spheres can be agglutinated extensively by concanavalin A, while another grade with the same binding constant is not affected. Photomicrographs and measurement by capillary suction show that deformability and good contact between these gel spheres can be correlated with their agglutinability.

摘要

右旋糖酐是一种能与伴刀豆球蛋白A相互作用的多糖，并且有在水中具有不同溶胀程度的不溶性右旋糖酐球。这些右旋糖酐凝胶球中的一种能被伴刀豆球蛋白A广泛凝集，而具有相同结合常数的另一种则不受影响。显微照片和毛细管抽吸测量表明，这些凝胶球的可变形性和良好接触与它们的凝集性相关。