Burry R W
Brain Res. 1980 Feb 17;184(1):85-98. doi: 10.1016/0006-8993(80)90588-0.
Neuronal cell processes in dispersed cell culture grow out onto Sepharose beads coated with poly-basic proteins. Apparent presynaptic elements are formed by these neuronal processes with the bead serving as a postsynaptic element. It is suggested that electrostatic binding between poly-acidic groups on the presynaptic element and poly-basic troups on the postsynaptic element is one of the initial steps in the formation of a synaptic contact in culture.
在分散细胞培养中，神经元细胞突起生长到包被有多元碱性蛋白的琼脂糖珠上。这些神经元突起以珠子作为突触后元件形成明显的突触前元件。有人提出，突触前元件上的多酸性基团与突触后元件上的多碱性基团之间的静电结合是培养中突触接触形成的初始步骤之一。
