从牙龈二氧化碳嗜纤维菌中检测成纤维细胞增殖抑制因子。
Detection of a fibroblast proliferation inhibitory factor from Capnocytophaga sputigena.
作者信息
Stevens R H, Sela M N, Shapira J, Hammond B F
出版信息
Infect Immun. 1980 Jan;27(1):271-5. doi: 10.1128/iai.27.1.271-275.1980.
Abstract
The addition of a sonic extract of Capnocytophaga sputigena to the culture fluid to human fibroblasts resulted in an inhibition of cell proliferation. The inhibition was dose-related (200 micrograms/ml caused a 90% inhibition, and 1,000 micrograms/ml caused a complete cessation of growth). The growth inhibition was not due to alterations in culture medium, pH or ionic strength, or to the effects of the C. sputigena lipopolysaccharide.
摘要
将生痰二氧化碳嗜纤维菌的超声提取物添加到人类成纤维细胞的培养液中会导致细胞增殖受到抑制。这种抑制作用与剂量相关（200微克/毫升会导致90%的抑制，1000微克/毫升会导致生长完全停止）。生长抑制并非由于培养基、pH值或离子强度的改变，也不是由于生痰二氧化碳嗜纤维菌脂多糖的作用。
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