Wu K K, Collon D J, Guise E R
J Bone Joint Surg Am. 1980 Mar;62(2):189-94.
In this paper we present five new cases and review sixty-one reported cases of extra-osseous chondrosarcoma. The lesion has a predilection for middle-aged men and for localization in the extremities. The mild and delayed nature of the symptoms contributes to delayed or inadequate treatment and an unusually high over-all recurrence rate of 50 per cent. En bloc resection is the treatment of choice. Amputation should be reserved for large tumors with extensive or intra-articular invasion, osseous erosion, or major neurovascular involvement. Pulmonary lobectomy appears to be effective in treating localized pulmonary metastasis. Chemotherapy and radiotherapy can also provide palliative benefits to patients with widespread metastases. Nearly all (77.8 per cent) of the known disease-related fatalities took place during the first year after operation on the primary tumor. The over-all five-year survival rate most likely is less than 81.2 per cent.
在本文中，我们报告了5例新的骨外软骨肉瘤病例，并回顾了61例已报道的病例。该病变好发于中年男性，且多位于四肢。症状的轻微性和延迟性导致治疗延迟或不充分，总体复发率异常高，达50%。整块切除是首选的治疗方法。对于侵犯范围广泛、累及关节内、有骨质侵蚀或主要神经血管受累的大肿瘤，应考虑截肢。肺叶切除术似乎对治疗局限性肺转移有效。化疗和放疗也可为广泛转移的患者提供姑息性疗效。几乎所有（77.8%）已知的与疾病相关的死亡都发生在原发肿瘤手术后的第一年。总体五年生存率很可能低于81.2%。
