Disler D G, Rosenberg A E, Springfield D, O'Connell J X, Rosenthal D I, Kattapuram S V
Department of Radiology, Massachusetts General Hospital, Boston 02114.
Skeletal Radiol. 1993 Nov;22(8):595-9. doi: 10.1007/BF00197142.
Among 251 patients who presented to our orthopedic oncology unit over the last 20 years with chondrosarcoma, we identified two patients with low to intermediate grade conventional chondrosarcoma who developed multifocal bone metastases in the absence of pulmonary spread. The metastatic lesions were of a similar histologic grade to the primary site. One of the patients had synchronous foci, while the other developed the bone lesions 3 years after initial presentation. The unusual behavior of these cases, as well as the possibility that they may represent instances of multicentric chondrosarcoma, is discussed.
在过去20年里，有251例软骨肉瘤患者前来我们的骨肿瘤科室就诊，我们发现其中2例低至中级别传统型软骨肉瘤患者在没有肺转移的情况下发生了多灶性骨转移。转移病灶的组织学分级与原发部位相似。其中1例患者有同步病灶，另1例在初次就诊3年后出现骨病变。本文讨论了这些病例的异常表现，以及它们可能代表多中心软骨肉瘤的可能性。
