Komatsu S, Sato T, Katakura R, Sakurai Y, Wada T, Namiki T
No Shinkei Geka. 1980 Feb;8(2):187-91.
A case of medulloblastoma with pulmonary metastasis was reported. The patient was a 9-year old female who was diagnosed as cerebellar medulloblastoma and treated by total removal of the tumor with adjuvant radiotherapy. The recurrence occurred and the expired 4 months after surgery. The entire clinical course was 2 1/2 years. Autopsy revealed a secondary focus of medulloblastoma in the upper lobe of right lung. No residural tumor was found in the brain. In the literature, 54 cases of extracranial metastasis of medulloblastoma was reported. Only eight of which lead metastatic deposits in the lung. We discussed the possible routes and sites of metastasis in relation to the treatment and prognosis on these cases who showed extracranial metastasis of medulloblastoma.
报告了1例髓母细胞瘤伴肺转移的病例。患者为9岁女性,被诊断为小脑髓母细胞瘤,并接受了肿瘤全切及辅助放疗。术后复发,术后4个月死亡。整个临床病程为2年半。尸检发现右肺上叶有髓母细胞瘤转移灶。脑部未发现残留肿瘤。文献报道了54例髓母细胞瘤颅外转移的病例。其中只有8例出现肺部转移灶。我们讨论了这些出现髓母细胞瘤颅外转移病例的可能转移途径和部位及其与治疗和预后的关系。