Breuer A C, Kneisley L W, Fischer E G
Spine (Phila Pa 1976). 1980 Jan-Feb;5(1):19-22.
The Brown-Séquard syndrome is infrequently reported. Though widely considered indicative of intramedullary spinal cord disease, in the absence of penetrating spinal cord trauma, the syndrome is frequently an early stage of extramedullary spinal cord compression, as an extensive analysis of diverse literatures reveals. We describe two cases resulting from compression of the spinal cord by a meningioma. While previous reviews emphasize that radicular or vertebral pain is a prominent feature of spinal cord compression by intradural tumors, our patients had no pain referable to tumor. Awareness that painless extramedullary spinal cord compression can produce the Brown-Séquard syndrome, early myelography, and surgical intervention are necessary to prevent progressive deficit. Even when encountered in a patient who has previously well-documented demyelinating disease, the syndrome should not be written off as a relatively untreatable intramedullary process.
布朗-塞卡尔综合征的报道较少。尽管普遍认为该综合征提示脊髓髓内疾病，但在无穿透性脊髓损伤的情况下，正如对各种文献的广泛分析所揭示的，该综合征常为脊髓髓外压迫的早期阶段。我们描述了两例因脑膜瘤压迫脊髓导致的病例。虽然既往综述强调神经根性或椎骨疼痛是硬膜内肿瘤压迫脊髓的突出特征，但我们的患者并无与肿瘤相关的疼痛。认识到无痛性脊髓髓外压迫可导致布朗-塞卡尔综合征，早期脊髓造影及手术干预对于预防神经功能进行性缺损是必要的。即使在先前有明确记录的脱髓鞘疾病患者中出现该综合征，也不应将其视为相对无法治疗的髓内病变而不予理会。
