Guidetti B, Spallone A
Surg Neurol. 1980 Jan;13(1):9-17.
This paper analyzes the clinical, diagnostic and surgical data of 18 benign extramedullary tumors at the foramen magnum extending into the posterior fossa and the spinal canal. These cases represent 30% of 60 foramen magnum tumors operated on between 1952 and 1978, among 4187 brain tumors and 587 tumors of the spinal cord. Foramen magnum meningiomas constitute 11 of this series (1.2% of 873 meningiomas, 113 of which were spinal). The considerable difficulty in early diagnosis is emphasized. However, in the present series, myelography showed positive findings in all cases, and angiography in most of them. CT scan, performed in one case, demonstrated the lesion. Surgical mortality was 11% (two deaths). On both patients who died after the operation, multiple surgical procedures had been performed because of erroneous diagnoses made in another unit. At the time of operation neurological symptoms were very advanced, and large tumors were located anteriorly. The review of the remaining patients showed a regression of preoperative symptoms with good to excellent results in all. No recurrences were recorded.
本文分析了18例延伸至后颅窝及椎管的枕大孔区良性髓外肿瘤的临床、诊断及手术资料。这些病例占1952年至1978年间所施行手术的60例枕大孔区肿瘤的30%,这60例枕大孔区肿瘤来自4187例脑肿瘤及587例脊髓肿瘤。本系列中有11例为枕大孔区脑膜瘤(占873例脑膜瘤的1.2%,其中113例为脊髓脑膜瘤)。文中强调了早期诊断存在的巨大困难。然而,在本系列中,脊髓造影在所有病例中均显示阳性结果,血管造影在大多数病例中显示阳性。1例患者进行了CT扫描,显示了病变。手术死亡率为11%(2例死亡)。术后死亡的2例患者均因另一科室的错误诊断而进行了多次手术。手术时神经症状已非常严重,且巨大肿瘤位于前方。对其余患者的复查显示术前症状均有缓解,效果良好至极佳。无复发记录。