Voronova L A, Ivanov S D, Zabezhinskiĭ M A
Vopr Onkol. 1980;26(2):58-62.
The development of hepatocellular tumors in rats would show the same character and was observed in the same period (6 months) after either simultaneous administration of a hepatocarcinogen--diethylnitrosoamine (0.02%) and a possible antitumor agent, namely hydrazine sulfate (0.012%) with drinking water, or after the administration of the hepatocarcinogen concerned alone. Hydrazine sulfate failed to reveal any anti-carcinogenic properties, but it would normalize the turnover rate of total RNA and its nuclear components in the rat liver tissue.
大鼠肝细胞肿瘤的发展会呈现相同特征，且在同时给予肝癌致癌物——二乙基亚硝胺（0.02%）和一种可能的抗肿瘤剂（即硫酸肼，0.012%）并与饮用水混合，或单独给予相关肝癌致癌物后的同一时期（6个月）被观察到。硫酸肼未显示出任何抗癌特性，但它能使大鼠肝组织中总RNA及其核成分的周转率正常化。
