Retailliau H F, Curtis A C, Storr G, Caesar G, Eddins D L, Hattwick M A
Am J Epidemiol. 1980 Mar;111(3):270-8. doi: 10.1093/oxfordjournals.aje.a112896.
In 1976, the Center for Disease Control coordinated nationwide surveillance for illnesses after influenza vaccination as part of an effort to vaccinate the nation against influenza A/New Jersey/76. For the 48,161,019 persons vaccinated in 1976, a total of 4733 reports of illness were received which included reports of 223 deaths. When Guillain-Barré syndrome was reported in vaccine recipients, an investigation was begun to examine this possible association. Other than the Guillain-Barré syndrome and rare cases of anaphylaxis, no serious illnesses were causally associated with influenza vaccination by this type of surveillance. Widespread underreporting of illness and death in the passive phase of this surveillance system, however, impaired the ability to draw conclusions about reactions to vaccine from the reports of illness received.
1976年，疾病控制中心协调了全国范围内针对流感疫苗接种后疾病的监测工作，作为全国性甲型流感/新泽西/76疫苗接种工作的一部分。在1976年接种疫苗的48,161,019人中，共收到4733份疾病报告，其中包括223例死亡报告。当疫苗接种者中报告出现格林-巴利综合征时，便开始了一项调查以研究这种可能的关联。除格林-巴利综合征和罕见的过敏反应病例外，通过这种监测方式未发现其他严重疾病与流感疫苗接种存在因果关系。然而，该监测系统被动阶段对疾病和死亡情况的普遍漏报，削弱了根据所收到的疾病报告得出关于疫苗反应结论的能力。
