Cibull M L, Gray G F
Am J Surg Pathol. 1978 Dec;2(4):401-5. doi: 10.1097/00000478-197812000-00006.
An aggressive anaplastic tumor of the thyroid with osteoclastoma-like giant cells was studied by electron microscopy. The lack of junctional complexes or other obvious epithelial elements suggested mesenchymal origin. The giant cells resembled osteoclasts with respect to mitochondria, rough endoplastic reticulum, lysosomes, ribosome complexes and vacuoles, but the prominent nuclear golgi apparatus of giant cell tumors of bone was absent.
对一例伴有破骨细胞瘤样巨细胞的侵袭性甲状腺间变性肿瘤进行了电镜研究。缺乏连接复合体或其他明显的上皮成分提示其起源于间充质。巨细胞在线粒体、粗面内质网、溶酶体、核糖体复合体和液泡方面类似于破骨细胞，但缺乏骨巨细胞瘤中显著的核高尔基体。
