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伴有破骨细胞样巨细胞的肺未分化癌

Undifferentiated carcinoma of the lung with osteoclast-like giant cells.

作者信息

Nakahashi H, Tsuneyoshi M, Ishida T, Minagawa S, Owaki Y, Momii S, Eimoto T

出版信息

Jpn J Surg. 1987 May;17(3):199-203. doi: 10.1007/BF02470600.

DOI:10.1007/BF02470600
PMID:3626216
Abstract

We treated a patient with undifferentiated carcinoma of the lung, with osteoclast-like giant cells resembling those of the giant cell tumor of bone. The clinical and morphologic characteristics of this case are documented, and the literature concerning this type of tumor is reviewed. The tumor differed histologically from the pleomorphic carcinoma, which occurs most commonly in the lung, and showed diverse pleomorphic manifestation with benign looking osteoclast-like multinucleated cells and bizarre giant cells. In addition, and undifferentiated carcinoma with a sarcoma-like appearance containing small areas of papillary adenocarcinoma was evident in the tumor.

摘要

我们治疗了一名患有肺未分化癌的患者,其具有类似骨巨细胞瘤的破骨细胞样巨细胞。记录了该病例的临床和形态学特征,并对有关此类肿瘤的文献进行了综述。该肿瘤在组织学上与最常见于肺部的多形性癌不同,表现出多种多形性表现,包括看似良性的破骨细胞样多核细胞和奇异巨细胞。此外,肿瘤中可见具有肉瘤样外观且含有小灶乳头状腺癌的未分化癌。

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1
Undifferentiated carcinoma of the lung with osteoclast-like giant cells.伴有破骨细胞样巨细胞的肺未分化癌
Jpn J Surg. 1987 May;17(3):199-203. doi: 10.1007/BF02470600.
2
Squamous cell carcinoma of lung associated with osteoclast-like giant cells: report of a case.肺鳞状细胞癌伴破骨细胞样巨细胞:一例报告。
Int J Clin Exp Pathol. 2015 Sep 1;8(9):11823-5. eCollection 2015.
3
[Undifferentiated carcinoma of the thyroid gland with osteoclast-like giant cells--a case report].[伴有破骨细胞样巨细胞的甲状腺未分化癌——病例报告]
Gan No Rinsho. 1984 Oct;30(13):1700-6.
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Anaplastic carcinoma of the thyroid with osteoclast-like giant cells.伴有破骨细胞样巨细胞的甲状腺间变性癌。
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Pleomorphic carcinoma of the pancreas: an analysis of 15 cases.胰腺多形性癌:15例病例分析
Cancer. 1977 May;39(5):2114-26. doi: 10.1002/1097-0142(197705)39:5<2114::aid-cncr2820390528>3.0.co;2-3.
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Non-Small Cell Carcinoma of the Lung With Osteoclast-Like Giant Cells.伴有破骨细胞样巨细胞的肺非小细胞癌
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Mammary carcinoma with osteoclast-like giant cells. A study of eight cases with follow-up data.伴有破骨细胞样巨细胞的乳腺癌。8例随访资料研究。
Am J Clin Pathol. 1979 Sep;72(3):383-9. doi: 10.1093/ajcp/72.3.383.
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Osteoclast-rich undifferentiated carcinomas of the urinary tract.富含破骨细胞的泌尿道未分化癌。
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Endoscopic ultrasound-guided fine-needle aspiration of undifferentiated carcinoma with osteoclast-like giant cells of the pancreas: a report of 2 cases with literature review.内镜超声引导下细针穿刺胰腺破骨细胞样巨细胞未分化癌:附2例报告并文献复习
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Osteoclast-like giant cell tumor of the renal pelvis associated with urothelial carcinoma: computed tomography, gross, and histologic appearance.肾盂骨巨细胞瘤伴尿路上皮癌:CT、大体和组织学表现。
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Neural is Fundamental: Neural Stemness as the Ground State of Cell Tumorigenicity and Differentiation Potential.神经是基础:神经干细胞作为细胞肿瘤发生和分化潜能的基础状态。
Stem Cell Rev Rep. 2022 Jan;18(1):37-55. doi: 10.1007/s12015-021-10275-y. Epub 2021 Oct 29.
2
Non-Small Cell Carcinoma of the Lung With Osteoclast-Like Giant Cells.伴有破骨细胞样巨细胞的肺非小细胞癌
Int J Surg Pathol. 2017 May;25(3):258-261. doi: 10.1177/1066896916679519. Epub 2016 Nov 29.
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Numerous osteoclast-like giant cells in metastases from lung adenocarcinoma, but absent from primary tumor.

本文引用的文献

1
Unidifferentiated carcinoma of the thyroid gland with osteoclast-like giant cells.伴有破骨细胞样巨细胞的甲状腺未分化癌。
Acta Pathol Jpn. 1980 Mar;30(2):323-34. doi: 10.1111/j.1440-1827.1980.tb01327.x.
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Carcinoma of the breast with stromal epulis-like giant cells.伴有间质龈瘤样巨细胞的乳腺癌
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3
Osteoclastoma-like giant cell tumor of the liver.肝脏骨巨细胞瘤样巨细胞肿瘤
肺腺癌转移灶中存在大量破骨细胞样巨细胞,但原发肿瘤中不存在。
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Osteoclastoma-like Giant Cell Tumor of the Lung.肺破骨细胞瘤样巨细胞瘤
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Breast cancer with osteoclast-like multinucleated giant cells.伴有破骨细胞样多核巨细胞的乳腺癌。
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Hepatocellular carcinoma with osteoclast-like giant cells.伴有破骨细胞样巨细胞的肝细胞癌
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Hum Pathol. 1983 Nov;14(11):1004-6. doi: 10.1016/s0046-8177(83)80181-6.
7
Carcinoma of pancreas simulating giant cell tumor of bone. Electron-microscopic evidence of its acinar cell origin.胰腺癌细胞模拟骨巨细胞瘤。其腺泡细胞起源的电镜证据。
Cancer. 1968 Aug;22(2):333-44. doi: 10.1002/1097-0142(196808)22:2<333::aid-cncr2820220210>3.0.co;2-a.
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Osteoclastoma-like giant cell tumor of the thyroid. Report of a case with prolonged survival following partial excision and radiotherapy.
Cancer. 1973 Mar;31(3):621-5. doi: 10.1002/1097-0142(197303)31:3<621::aid-cncr2820310319>3.0.co;2-n.
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Ovarian giant cell tumor with cystadenocarcinoma.伴有囊腺癌的卵巢巨细胞瘤。
Arch Pathol. 1975 Sep;99(9):488-91.
10
Metaplastic squamous cell carcinoma of bronchus simulating giant cell tumor of bone.模拟骨巨细胞瘤的支气管化生鳞状细胞癌
Cancer. 1977 Mar;39(3):1119-28. doi: 10.1002/1097-0142(197703)39:3<1119::aid-cncr2820390317>3.0.co;2-7.