Nakahashi H, Tsuneyoshi M, Ishida T, Minagawa S, Owaki Y, Momii S, Eimoto T
Jpn J Surg. 1987 May;17(3):199-203. doi: 10.1007/BF02470600.
We treated a patient with undifferentiated carcinoma of the lung, with osteoclast-like giant cells resembling those of the giant cell tumor of bone. The clinical and morphologic characteristics of this case are documented, and the literature concerning this type of tumor is reviewed. The tumor differed histologically from the pleomorphic carcinoma, which occurs most commonly in the lung, and showed diverse pleomorphic manifestation with benign looking osteoclast-like multinucleated cells and bizarre giant cells. In addition, and undifferentiated carcinoma with a sarcoma-like appearance containing small areas of papillary adenocarcinoma was evident in the tumor.
我们治疗了一名患有肺未分化癌的患者,其具有类似骨巨细胞瘤的破骨细胞样巨细胞。记录了该病例的临床和形态学特征,并对有关此类肿瘤的文献进行了综述。该肿瘤在组织学上与最常见于肺部的多形性癌不同,表现出多种多形性表现,包括看似良性的破骨细胞样多核细胞和奇异巨细胞。此外,肿瘤中可见具有肉瘤样外观且含有小灶乳头状腺癌的未分化癌。