Malone J M, Bean B, Laguna J, Hamilton R, Labadie E, Moore W S
Ann Surg. 1980 Mar;191(3):347-54. doi: 10.1097/00000658-198003000-00015.
Both Doppler supraorbital examination (OSM) and oculoplethysmography (OPG) were administered to 101 patients (202 arteries) to document the presence or absence of hemodynamically significant lesions of the internal carotid artery prior to angiography. There was no significant difference between the OSM and OPG with respect to diagnostic sensitivity or specificity, incidence of false-negative or false-positive results, and overall diagnostic accuracy. The diagnostic accuracy for the OSM and the OPG were 94.2% and 91.6%, respectively. In 171/202 (84.6%) arteries, the OSM and OPG were in diagnostic agreement, and the overall diagnostic accuracy of the combined tests was 97%. However, when the OSM and OPG did not agree (31/202 arteries, 15.4%), the diagnostic accuracy of neither the OSM nor the OPG was acceptable. Although the best diagnostic accuracy was obtained using two means of noninvasive cerebrovascular testing, in those instances where only one test may be available, the OPG would appear to be the test of choice. In those laboratories in which high diagnostic accuracy is obtained with the OSM, the addition of OPG testing will increase the overall diagnostic accuracy to a very high level. The presence of a midcervical bruit was found to have a very poor correlation with the incidence of hemodynamically significant stenoses of the internal carotid artery. Although both the OSM and OPG have minimal value in patients with symptomatic cerebrovascular disease, these tests play a very important role in screening patients for asymptomatic carotid stenosis or atypical cerebrovascular symptoms.
对101例患者(202条动脉)进行了眶上多普勒检查(OSM)和眼体积描记法(OPG),以在血管造影术前记录颈内动脉是否存在血流动力学显著病变。OSM和OPG在诊断敏感性或特异性、假阴性或假阳性结果的发生率以及总体诊断准确性方面没有显著差异。OSM和OPG的诊断准确性分别为94.2%和91.6%。在202条动脉中的171条(84.6%)中,OSM和OPG诊断结果一致,联合检查的总体诊断准确性为97%。然而,当OSM和OPG结果不一致时(202条动脉中的31条,15.4%),OSM和OPG的诊断准确性均不可接受。虽然使用两种无创脑血管检测方法可获得最佳诊断准确性,但在只能进行一种检测的情况下,OPG似乎是首选检测方法。在那些使用OSM能获得高诊断准确性的实验室中,增加OPG检测将使总体诊断准确性提高到非常高的水平。发现颈部中部杂音的存在与颈内动脉血流动力学显著狭窄的发生率相关性很差。虽然OSM和OPG对有症状的脑血管疾病患者价值极小,但这些检测在筛查无症状颈动脉狭窄或非典型脑血管症状的患者中起着非常重要的作用。