Renal involvement in human trichinosis.

A renal clinicopathologic study was made in five patients with trichinosis. The patients had mild proteinuria and abnormal urinary sediment that disappeared after the disease was under control. Creatinine clearance was normal in all cases. p-Aminohippurate clearance was decreased in two patients who had hypoalbuminemia. A renal biopsy specimen showed mesangial proliferative glomerulonephritis with deposition of immunoglobulins and C3 in the mesangial areas and along the capillary loops. Glomerular fibrin deposition was noted in one case. Deposition of hyaline material and C3 was observed in the arteriolar wall. Tubular interstitial changes were not present.